SPELL - S. cerevisiae

Citation	Terzioglu E, Alkim C, Arslan M, Balaban BG, Holyavkin C, Kisakesen HI, Topaloglu A, Yilmaz Sahin U, Gunduz Isik S, Akman S, Cakar ZP. Genomic, transcriptomic and physiological analyses of silver-resistant Saccharomyces cerevisiae obtained by evolutionary engineering. Yeast (Chichester, England), 2020.
PubMed ID	33464648
Short Description	Transcriptomic analysis of silver-resistant Saccharomyces cerevisiae mutant obtained by evolutionary engineering
# of Conditions	6
Full Description	Silver-resistant Saccharomyces cerevisiae mutant was obtained by evolutionary engineering method. Briefly, genetic diversity in reference strain, CEN.PK.113-7D, was increased by ethyl methane sulfonate (EMS)-mutagenesis. The mutant population was passaged several times in gradually increasing silver stress. Several mutant individuals were selected from the final population. Among selected mutant individuals, one of them was much more resistant to silver stress than the reference strain, called as 2E. Whole-genome transcriptomic analysis was performed to identify the silver resistance mechanisms in the silver-resistant mutant strain.
Tags	metal or metalloid ion stress