SPELL - S. cerevisiae

Citation	Chen L, Wang M, Hou J, Fu J, Shen Y, Liu F, Zhang Z, Bao X . HAL2 overexpression induces iron acquisition in bdf1_ cells and enhances their salt resistance. Curr Genet, 2017.
PubMed ID	27387517
Short Description	HAL2 overexpression induces iron acquisition and enhanced salt resistance in bdf1delta
# of Conditions	5
Full Description	The strain bdf1_+HAL2 improved salt resistance of bdf1. To gain further insight into the mechanism of bdf1 salt sensitivity, DNA microarray analysis was performed to determine the reason for the salt sensitivity of bdf1 cells and the process of how HAL2 overexpression and HDA1 deletion improves salt resistance. Transcriptomic analysis under salt treatment (0.5 mol.L-1 NaCl for 45 min) was performed using four different strains: bdf1, W303, bdf1_+HAL2 and bdf1hda1. The transcription of 1,393 genes were significantly changed( > 2-fold) in bdf1 compared with W303 upon NaCl stress (0.5 mol.L-1 NaCl for 45 min). Only 108 genes were significantly changed ( > 2-fold) in bdf1_+HAL2 compared with bdf1 upon NaCl stress (0.5 mol.L-1 NaCl for 45 min). Only 88 genes were significantly changed ( > 2-fold) in bdf1_+HAL2 compared with bdf1 upon NaCl stress (0.5 mol.L-1 NaCl for 45 min).
Tags	osmotic stress