| Citation | Kugler KG, Jandric Z, Beyer R, Klopf E, Glaser W, Lemmens M, Shams M, Mayer K, Adam G, Schuller C . Ribosome quality control is a central protection mechanism for yeast exposed to deoxynivalenol and trichothecin BMC Genomics, 2016. |
| PubMed ID | 27245696 |
| Short Description | Ribosome quality control is a central protection mechanism for yeast exposed to Deoxynivalenol and Trichothecin |
| # of Conditions | 23 |
Full Description
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Trichothecenes, like deoxynivalenol (DON) are secondary metabolites of Fusarium species, and are major pollutants in cereal food and feed products. They inhibit eukaryotic protein synthesis, however with only partly resolved consequences for the cellular homeostasis. Here we report a systematic functional investigation of the effects of DON on exponential phase growing yeast cells using either short doses of DON or continuos treatment with DON. |
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