SPELL - S. cerevisiae

Citation	Iwahashi H, Odani M, Ishidou E, Kitagawa E. Adaptation of Saccharomyces cerevisiae to high hydrostatic pressure causing growth inhibition. FEBS letters, 2005.
PubMed ID	15876434
Short Description	Adaptation of Saccharomyces cerevisiae to high hydrostatic pressure causing growth inhibition.
# of Conditions	8
Full Description	Genome-wide mRNA expression profiles of Saccharomyces cerevisiae growing under hydrostatic pressure were characterized. We selected a hydrostatic pressure of 30 MPa at 25 degrees C because yeast cells were able to grow under these conditions, while cell size and complexity were increased after decompression. Functional characterization of pressure-induced genes suggests that genes involved in protein metabolism and membrane metabolism were induced. The response to 30 MPa was significantly different from that observed under lethal conditions because protein degradation was not activated under 30 MPa pressure. Strongly induced genes those that contribute to membrane metabolism and which are also induced by detergents, oils, and membrane stabilizers.
Tags	stress