SPELL - S. cerevisiae

Citation	Deshpande AA, Bhatia M, Laxman S, Bachhawat AK . Thiol trapping and metabolic redistribution of sulfur metabolites enable cells to overcome cysteine overload. Microb Cell, 2017.
PubMed ID	28435838
Short Description	Physiological response of S. cerevisiae excess cysteine or cystine
# of Conditions	8
Full Description	Excess cysteine (and cystine) is known to be toxic in organisms. Due to the absence of cysteine dioxygenase (involved in degradation of excess cysteine in humans and pathogenic fungi) in non pathogenic fungi such as S. cerevisiae, mechanism of cysteine (and cystine) tolerance is yet to be addressed.
Tags	amino acid metabolism, sulfur utilization